rabbit anti his6 hrp antibody (Cedarlane)
Structured Review
![The HPV16 genome and E6 oncoprotein. ( A ) The circular, double-stranded DNA genome (~7.9 kbp) consists of a long control region (LCR) which regulates viral transcription, as well as seven early ( E1 , E2 , E4 , E5 , E6 , E7 , and E8 ) and two late ( L1 and L2 ) genes. The proteins encoded by the early genes promote viral persistence, replication, and release, whereas those encoded by the late genes create the viral capsid [ , , ]. The HPV16 genome (GenBank Accession #: K02718.1) was visualized using the Pathogen–Host Analysis Tool . ( B ) The E6 oncoprotein (~18 kDa) contains two zinc-binding domains. It interacts with host proteins after first complexing with the hijacked ubiquitin ligase E6AP or via its C-terminal PDZ-binding motif, driving cancerous changes in infected cells [ , ]. ( C ) Schematic representation of the recombinant HPV16 E6 proteins used in this study. Their amino acid differences from the reference sequence (GenBank Accession #: K02718.1) as well as their respective polyhistidine <t>(His6)</t> tags and maltose binding protein (MBP) fusion partners are indicated.](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_9864/pmc06539864/pmc06539864__ijms-20-02088-g001.jpg)
Rabbit Anti His6 Hrp Antibody, supplied by Cedarlane, used in various techniques. Bioz Stars score: 93/100, based on 79 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rabbit+anti+his6+hrp+antibody/pmc06539864-187-11-16?v=Cedarlane
Average 93 stars, based on 79 article reviews
Images
1) Product Images from "Single-Domain Antibodies Represent Novel Alternatives to Monoclonal Antibodies as Targeting Agents against the Human Papillomavirus 16 E6 Protein"
Article Title: Single-Domain Antibodies Represent Novel Alternatives to Monoclonal Antibodies as Targeting Agents against the Human Papillomavirus 16 E6 Protein
Journal: International Journal of Molecular Sciences
doi: 10.3390/ijms20092088
Figure Legend Snippet: The HPV16 genome and E6 oncoprotein. ( A ) The circular, double-stranded DNA genome (~7.9 kbp) consists of a long control region (LCR) which regulates viral transcription, as well as seven early ( E1 , E2 , E4 , E5 , E6 , E7 , and E8 ) and two late ( L1 and L2 ) genes. The proteins encoded by the early genes promote viral persistence, replication, and release, whereas those encoded by the late genes create the viral capsid [ , , ]. The HPV16 genome (GenBank Accession #: K02718.1) was visualized using the Pathogen–Host Analysis Tool . ( B ) The E6 oncoprotein (~18 kDa) contains two zinc-binding domains. It interacts with host proteins after first complexing with the hijacked ubiquitin ligase E6AP or via its C-terminal PDZ-binding motif, driving cancerous changes in infected cells [ , ]. ( C ) Schematic representation of the recombinant HPV16 E6 proteins used in this study. Their amino acid differences from the reference sequence (GenBank Accession #: K02718.1) as well as their respective polyhistidine (His6) tags and maltose binding protein (MBP) fusion partners are indicated.
Techniques Used: Control, Binding Assay, Ubiquitin Proteomics, Infection, Recombinant, Sequencing